Tadalista Professional blocks PDE-5, which contributes to the maintenance of higher levels of cGMP in the penis and allows for extended relaxation of the smooth muscles and improved blood flow. This procedure is required during sexual stimulation to achieve and maintain an erection. An increase in cGMP relaxes the smooth muscles in the penile blood vessels, allowing more blood to reach the penis. The result of this increased blood flow is an erection. Start with the lowest dose that will still produce the desired results. Tadalista Professional should not be used frequently. When the time for the planned sexual activity approaches, take the medicine as directed. Do not use more than one pill in 24 hours. When a medication is used too often or incorrectly, it may cause significant anomalies and inadvertent health issues.