Antibody Isotype Switching
Immunoglobulin class switching occurs quickly in the human body following the activation of mature naive B cells, changing the production of IgM and IgD to IgG, IgE, or IgA. IgM is the first type of immunoglobulin to be created during an immune response. The immunoglobulins produced by B cells shift from being predominately IgM to IgG, IgE, or IgA classes as the immune response develops,...